Process development and quality attributes for the freeze-drying process in pharmaceuticals, biopharmaceuticals and nanomedicine delivery: a state-of-the-art review
Abstract Background Process intensification is a major hurdle in pharmaceutical process scale-up.Solvent removal strategies have limited the effectiveness of the overall stability of pharmaceutical formulations.The main aim of present review article is to focus on the use of the freeze-drying process in pharmaceuticals, biopharmaceuticals and nanod